070115250 SPECIAL TOPICS IN MEDICINAL CHEMISTRY & DRUG DESIGN ( 2 Crd.Hrs )

Pre-Requisites : 070114130, 070113111, 070112290

This course provides more details about the advanced topics that represent specific areas of medicinal chemistry and drug discovery. Case studies on clinical drugs will be discussed with major emphasis on their design, synthesis, reaction mechanisms and structure-activity relationship studies. This course is also designed to shed the light on computer-based methods, combinatorial chemistry, high-throughput screening, and database mining. It is proposed to introduce the knowledge of hit discovery, lead identification, lead optimization, target selection, and molecular recognition employing computer-aided drug design software.