070115270 BIOTHERAPY ( 2 Crd.Hrs )

Pre-Requisites : 070112370

The various biological systems used to generate therapeutic agents will be described. DNA engineering approach to produce recombinant vectors capable of expressing the desired agent in prokaryotic and Eukaryotic systems in vitro and in vivo will be discussed. Approaches of molecular manipulations of proteins to generate fusion, modied and highly stable agents will be strongly and deeply discussed. The production and applications of selected agents used in the treatment of various clinical complications will be clearly illustrated and discussed. Students will be required select an agent currently produced by pharmaceutical companies to present and discuss the relevant approach and production.