Hypolipidemic activity of extracts from eriobotrya japonica and Olea europaea, traditionally used in the Greco-Arab medicine in maintaining healthy fat levels in the blood

Loquat (Eriobotrya japonica) and olive leaves (Olea europaea) were investigated for their safety, anti-oxidant, and anti-hypercholesterolemic properties. Therefore, a fixed combination of dry extracts of Eriobotrya japonica and Olea europaea was prepared into so called Cholevel tablets and tested for safety and efficacy in vitro and in vivo tests. No sign of toxicity (LDH-release) was observed in cultured human fibroblasts incubated with increasing concentrations of Cholevel. Similar results were seen in MTT assay in co-cultures of ...