In vitro evaluation of the biofunctionality of osteoblasts cultured on DegraPol-foam

The biofunctionality of osteoblasts cultured on DegraPol-foam, a biodegradable, elastic, and
highly porous polyesterurethane-foam, was determined here to examine the possible use of
this structure as bone repair material. Osteoblasts from rat tibia and from the cell line
(MC3T3-E1) exhibited relatively high attachment and low doubling time that result in a
confluent cell multilayer on the surface of the foam. They produced high concentrations of
collagen type I and osteocalcin, and expressed increasing alkaline phosphatase activity. ...