Authors
Shahinaz Mahajna
Mohammad Azab
Hilal Zaid
Basheer Abo Farich
Feras Al Battah
Shiri Mashner
Bashar Saad
Pages From
165
Pages To
165
Journal Name
European Journal of Medicinal Plants
Volume
5
Issue
2
Abstract

Aim: Based on knowledge from traditional Greco-Arab herbal medicine, this in vitro study
aims to evaluate the cytotoxicity and the anti-inflammatory mechanism of Peganum harmala
(P. harmala) seeds by measuring the expression and release of both anti-inflammatory (IL-
10) and pro-inflammatory (IL-1, IL-2, IL-6 and TNF-α) cytokines in human THP-1-derived
macrophages. Methodology: Cells were treated with 1μg lipopolyssacharide/ml (LPS) in the
absence and presence of increasing concentrations of extracts from the P. harmala seeds ...