ISSN:
doi.org/10.17096/jiufd.24812
Journal Name:
J Istanbul Univ Fac Dent
Volume:
50
Issue:
1
Pages From:
59
To:
64
Date:
Tuesday, August 18, 2015
Keywords:
Bisphosphonate-related osteonecrosis of the jaw (BRON J); BRON J treatment; risk factors; dental implants
Abstract:
Bisphosphonate (BP) is one of the possible riskfactors
in the osteonecrosis of the jaw (ON J). Surgical
interventions during or after the course of treatment
by using BPs may expose the patient under this risk.
Animal studies, human studies, case reports, and
systematic reviews are used to show the relationship
between the use of bisphosphonates and dental
implants. In this review data about bisphosphonaterelated
osteonecrosis of the jaw (BRON J): incidence,
prevention and treatment modalities for the patients
who are scheduled for dental implant treatment plan
and who have been already treated by dental implants
will be investigated. Various views for the relationship
between dental implants and bisphosphonates will be
analyzed depending on the multifactors: duration,
route of uptake, dosage of the drug and patient’s other
medications that affect the effects of bisphosphonate.
All patients treated with this drug must be informed
about the risk of implant loss or possibility of
osteonecrosis.
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