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Biocompatibility of highly porous and biodegradable degrapol®-foam to osteoblasts: in vitro evaluations

Authors: 
B Saad, T HUBER, M Casotti, P Schmutz, M Welti, GK Uhlschmid, P Neuenschwander, UW Suter
Journal Name: 
Advances in science and technology
Volume: 
1
Issue: 
1
Pages From: 
453
To: 
460
Date: 
Friday, January 1, 1999
Abstract: 
Transplantation of isolated autologous cells cultured on biodegradable polymer scaffolds offer new hope in finding a better way to repair bone defects than the currently used autogenous-and allogenous grafts. Therefore, engineering of biomaterials that enhance osteoblast adhesion and growth is desirable. Three-dimensional polymer matrix systems have shown considerable promise for tissue regeneration because of their large surface area for cell attachment and minimal distances for diffusion of nutrients, ...