Journal Name:
Journal of Biomedical Materials Research Part A
Volume:
39
Issue:
4
Pages From:
594
To:
602
Date:
Sunday, March 15, 1998
Abstract:
Recently, a new class of biodegradable PHB-based polyesterurethane
(DegraPol/btc®) has been prepared and found to exhibit favorable cell and tissue
compatibility. The present study has been designed to evaluate the response of primary
isolated rat tibia osteoblasts to small crystalline particles of short-chain poly [(R)-3-
hydroxybutyric acid](PHB-P diameter: 2–20 μm), of fluorescent-labeled analogs (DPHP-P),
and of lysine methyl ester as possible degradation products of DegraPol/btc®. ...