Maintaining a physiological blood glucose level with ‘glucolevel’, a combination of four anti-diabetes plants used in the traditional Arab herbal medicine

Safety and anti-diabetic effects of Glucolevel, a mixture of dry extract of leaves of the Juglans
regia L, Olea europea L, Urtica dioica L and Atriplex halimus L were evaluated using in vivo
and in vitro test systems. No sign of toxic effects (using LDH assay) were seen in cultured
human fibroblasts treated with increasing concentrations of Glucolevel. Similar observations
were seen in vivo studies using rats (LD50: 25 g/kg). Anti-diabetic effects were evidenced by
the augmentation of glucose uptake by yeast cells (2-folds higher) and by inhibition of ...