The study aims to design a training program using whole-body resistance exercises for football players and to determine its effect on some physical and physiological variables (resting heart rate, maximal oxygen consumption, vital capacity) of the studied football players. The researchers employed an experimental method with a single-group design, utilizing pre-test, post-test, and follow-up measurements to suit the nature of the study. The total population of the research consists of players from the academies of Tubas Sports Club, aged between 18 -20 years, with a total of 25 players. The study sample was purposively selected from the players of Tubas Sports Club football academiesand included 16 players as the main sample and 9 players for exploratory study. In light of the study's objectives and hypotheses, the researchers concluded that the training program using whole-body resistance exercises had a positive effect on some physical capabilities, favoring the post-test measurement. It also positively impacted some physiological variables (resting heart rate, maximal oxygen consumption, vital capacity), favoring the post-test measurement. The mean and standard deviation of restingheart rate were 77.06 bpm and 1.56, respectively, while the mean and standard deviation of maximal oxygen consumption were 62.12 ml/kg/min and 1.41, respectively. The mean and standard deviation of vital capacity were 2.89 liters and 0.096, respectively. The researchers recommend the use of whole-body resistance exercises in training programs for football players in this age group due to its clear impact on certain physical and physiological variables under study. They also advocate for coaches' attention to incorporating whole-body resistance exercises into progressively challenging training regimens to make them more engaging