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Prof. Hilal Zaid Publications

Article
Date Title
2023 In Vivo and In Vitro Antidiabetic Efficacy of Aqueous and Methanolic Extracts of Orthosiphon Stamineus Benth
2023 Tinosporaside from Tinospora cordifolia encourages skeletal muscle glucose transport through both PI-3-kinase and AMPK-dependent mechanisms
2022 Computer-Aided Drug Design of Natural Candidates for the Treatment of Non-Communicable Diseases
2022 In Silico Evaluation for the Inhibitory Action of Curcumin Derivatives on the SARS-COV2
2022 Drug Discovery of Plausible Lead Natural Compounds That Target the Insulin Signaling Pathway: Bioinformatics Approaches
2022 Isolation, Identification and Pharmacological Effects of Mandragora autumnalis Fruit Flavonoids Fraction
2021 In vitro and in silico evaluation for the inhibitory action of O. basilicum methanol extract on alpha-glucosidase and alpha-amylase.
2021 Gundelia tournefortii: Fractionation, Chemical Composition and GLUT4 Translocation Enhancement in Muscle Cell Line
2021 β-Sitosterol-D-glucopyranoside mimics estrogenic properties and stimulates glucose utilization in skeletal muscle cells
2021 From inequitable to sustainable e-waste processing for reduction of impact on human health and the environment
2019 In Vitro Evaluation of the Potential Use of Propolis as a Multitarget Therapeutic Product: Physicochemical Properties, Chemical Composition, and Immunomodulatory, Antibacterial, and Anticancer Properties
2019 In vitro evaluation of chemically analyzed H.triquetrifolium extract efficacy in apoptosis induction and cell cycle arrest of HCT-116 colon cancer cell line.
2019 Portulaca oleracea L. extracts enhance GLUT4 translocation to the surface of muscle cells in insulin dependent and independent fashion
2019 Phosphorylation status of fetuin-A is critical for inhibition of insulin action and is correlated with obesity and insulin resistance
2019 In vitro evaluations of cytotoxicity of Abelmoschus esculentus L., Asparagus aphyllus L. and Crataegus azarolus L. extracts and their effects on GLUT4 membrane translocation on L6 muscle cells and blood glucose levels in mice. Advancement in Medicinal P
2019 Metabolic and Epigenetic Action Mechanisms of Antidiabetic Medicinal Plants
2018 Gundelia tournefortii anti-diabetic efficacy: Chemical composition and GLUT4 translocation
2018 Anti-diabetic Activity and Chemical Composition of Teucrium Polium L.
2017 Medicinal Plants and Natural Active Compounds for Cancer Chemoprevention/Chemotherapy
2017 In vitro evaluation of anti-inflammatory and antioxidant effects of Asparagus aphyllus L., Crataegus azarolus L., and Ephedra alata Decne.in monocultures and co-cultures of HepG2 and THP-1-derived macrophages
2016 Hypericum triquetrifolium Extracts Modulate IL-6, IL-10 and TNF-α Protein and mRNA Expression in LPS-Activated Human Peripheral Blood Mononuclear Cells and THP-1-Derived Macrophages
2016 In vitro evaluation of anti-diabetic activity and cytotoxicity of chemically analysed Ocimum basilicum extracts
2016 Analysis of PI3K pathway components in human cancers
2016 Cloning and characterization of γ-glutamylcysteine synthetase in the salt-and oxidative stress-tolerant wild tomato species Solanum pennellii under abiotic stresses
2016 Natural Active Ingredients for Diabetes and Metabolism Disorders Treatment
2016 In silico modeling techniques for predicting the tertiary structure of human H4 receptor
2015 Medicinal plants and natural active compounds for diabetes and/or obesity treatmen
2015 In vitro Assessments of Cytotoxic and Cytostatic Effects of Asparagus aphyllus, Crataegus aronia , and Ephedra alata in Monocultures and Co-Cultures of Hepg2 and THP-1-Derived Macrophages
2015 In vitro evaluations of cytotoxicity and anti-inflammatory effects of Peganum harmala seed extracts in THP-1-derived macrophages
2013 In vitro evaluations of cytotoxicity of eight antidiabetic medicinal plants and their effect on GLUT4 translocation
2013 Novel excitation-contraction uncoupled RYR1 mutations in patients with central core disease
2013 Indexing molecules for their hERG liability
2012 Computerized techniques for modeling 3D structure of H4 receptor
2011 Greco-Arab and Islamic herbal-derived anti-cancer modalities: From tradition to molecular mechanisms
2011 Diabetes prevention and treatment with Greco-Arab and Islamic-based natural products
2011 Arab and Islamic herbal Cancer treatment
2010 Physicochemical Properties of Natural Based Cancer treatment by GrecoArab and Islamic herbal medicineProducts versus Synthetic Chemicals
2010 Physicochemical Properties of Natural Based Products versus Synthetic Chemicals
2010 Cancer treatment in the Arab-Islamic medicine: Integration of tradition with modern experimental trails
2010 Cancer treatment in the Arab-Islamic medicine: Integration of tradition with modern experimental trails
2009 GAPDH binds GLUT4 reciprocally to Hexokinase-II and regulates glucose transport activity
2008 Alpha-actinin-4 is selectively required for insulin-induced GLUT4 translocation
2008 Insulin action on glucose transporters through molecular switches, tracks and tethers
2008 Uncovering the role of VDAC in the regulation of cell life and death
2008 Hexokinase-I protection against apoptotic cell death is14 mediated via interaction with the Voltage Dependent Anion Channel-1: mapping the site of binding
2008 Mapping the ruthenium red-binding site of the voltage-dependent anion channel-1
2007 Localization of the Voltage-Dependent Anion Channel-1 Ca2+- Binding Sites
2006 Nucleotide-binding sites in the voltage-dependent anion channel: Characterization and localization
2005 The voltage-dependent anion channel modulates apoptotic cell death
2001 Calcium binding and translocation by voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function
Book
Date Title
2017 Anti-diabetes and Antiobesity Medicinal Plants and Phytochemicals: Safety, Efficacy, and Action Mechanisms
Book Chapter
Date Title
2012 State of the Art of Diabetes Treatment in Greco-Arab and Islamic Medicine
2012 Tradition and Perspectives of Diabetes Treatment in Greco-Arab and Islamic Medicine
2011 Greco-Arab and Islamic herbal medicine and cancer treatment/prevention
Conference Paper
Date Title
2019 Evaluation of the anti-diabetic medicinal plants fractions and phytochemicals efficacy in vitro and in vivo
2019 H.triquetrifolium Potential Anti Cancer Activity: Apoptosis Induction and Cell Cycle Arrest of Colon Cancer Cell Line and Chemical Analysis
2019 Greco-Arab herbs as a source of anti-diabetic compounds.
2019 Antidiabetic Activity of selected Mediterranean medicinal plants
2019 GLUT4 translocation test for Portulaca oleraceaL. extracts: In vitro evaluations of their anti- diabetic activity and cytotoxicity.
2019 Medicinal plants and phytochemicals: A source for GLUT4 stimulators and digestive enzymes inhibitors
2018 Abelmoschus esculentus L. and Asparagus aphyllus L. regulate blood glucose levels by improving GLUT4 membrane translocation: An In vivo and in vitro study.
2018 Novel anti diabetic phytochemicals: Isolation, protein target and mechanisms of action. 27th European Diabetes Congress,
2018 Cichorium pumilum as a source of anti-diabetic compounds: Chemical composition, cytotoxicity and GLUT4 translocation.
2017 Fetuin-A phosphorylation (Ser312) is critical for inhibition of insulin action and is correlated with obesity and insulin resistance
2017 Medicinal plants anti diabetic active ingredients: isolation, protein target and mechanism(s) of action
2016 Isolation and identification of the anti-diabetic phytochemicals in O. basilicum: unravelling their mechanism of action
2016 Medicinal plants anti diabetic active ingredients: isolation, protein target and action mechanism: Ocimum basilicum as a model
2016 Evaluation of anti-inflammatory and antioxidant effects of Asparagus aphyllus L., Crataegus azarolus L., and Ephedra alata Decne. in monocultures and cocultures
2016 Assessment of antioxidant and anti-inflammatory properties of Palestinian medicinal plants using monocultures and co-cultures of monocytes and hepatocytes
2016 In vitro evaluations of antihypoglycemic, cytotoxicity and chemical identification of methanolic sweet basil extract
2016 Chemical Composition, Cytotoxicity, Antibacterial and Anti-diabetic Activities of Teucrium polium L. Extracts
2016 Characterization of - glutamylcysteine synthetase in the salt- and oxidative stress-tolerant wild tomato species Lycopersicon pennellii under abiotic stresses
2015 Peganumharmala seed extract modulates anti-inflammatory and pro-inflammatory cytokines release in THP-1-derived macrophages
2015 Cytotoxic and cytostatic activity of Asparagus aphyllus, Crataegus aronia and Ephedra alata in hepatocytes and THP-1-derived macrophages in mono- and co-cultures in vitro
2014 Cytotoxic and apoptotic effects of Arum palaestinum and Peganum harmala
2014 in vitro antidiabetic Activity of three medicinal plants
2014 Atriplexm, Trigonella foenum-graecum and Urtica dioica enhance glucose disposal by skeletal muscle
2014 Peganumharmala seed extracts promotes anti-inflammatory responses in THP-1-derived macrophages
2014 Pergamum harmala and Hypericum triquetrifolium extracts induce apoptosis in human colon cancer cells through activation caspase 3
2013 Diabetes type II among Arab women: Prevalence and medicinal treatment
2012 In-vitro evaluation of safety and efficacy of Greco-Arab and Islamic-based antidiabetic medicinal plants
2012 The The anti-psoriatic effects of Hypericum triquetrifolium and Peganum harmale -derived factors are mediated by down regulation of pro-inflammatory cytokines and up regulation of apoptosis
2012 Anti-Oxidative and anti-diabetic plants action mechanism
2011 Obesity and diabetes: Morbidity and Treatment with Herbal Medicine
2010 Anti-Inflammatory effects of herbal-derived factors are mediated by down regulation of pro-inflammatory cytokines
2010 Palestinian Plants Increase glucose disposal by skeletal muscle cell line
2010 Arab Herbal Medicine-based Combination of Four Anti-Diabetes Plants Stabilizes a Physiological Blood Glucose Level
2010 The anti-psoriatic effects of herbal-derived factors as new drugs for combined psoriasis therapies
2007 GAPDH and Hexokinase-II interaction with GLUT4: A possible GLUT4-Metabolon
2006 GAPDH-GLUT4 interaction: characterization and possible function in insulin-regulated glucose uptake
2006 Characterization of GLUT4-GAPDH binding sites and possible implications for glucose uptake
2005 Identification of Hexokinase-I and ruthenium red binding sites in the Voltage Dependent Anion Channel
2005 Azido ruthenium specific labeling of Ca2+-binding proteins and localization of VDAC Ca2+- binding sites
2005 A single mutation in VDAC prevents the interaction of hexokinase and ruthenium red with VDAC and their protective effect against apoptotic cell death
2005 The voltage-dependent anion channel modulates apoptotic cell death
2004 The voltage-dependent anion channel modulates apoptotic cell death
2004 The voltage-dependent anion channel modulates apoptotic cell death
2003 Divalent Cation/Calcium Binding Sites in VDAC: Identification, Localization and Function in the Regulation of the channel Activities
2002 divalent cations binding and modulation of VDAC
2002 VDAC possesses ATP and divalent cations binding sites that regulate mitochondrial PT
2002 divalent cations binding and modulation of VDAC
2000 Calcium binding and translocation by VDAC: a possible regulatory mechanism in mitochondrial function
2000 Calcium translocation and binding by VDAC as a possible regulatory mechanism in mitochondrial function
2000 Calcium binding and translocation by VDAC: a possible regulatory mechanism in mitochondrial function
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