This study aimed to estimate spiritual well-being, psychological well-being, and quality of life among patients undergoing hemodialysis sessions in the West Bank. This descriptive study examined a random sample of 413 Palestinian patients receiving hemodialysis sessions in eleven centers operating in the West Bank. The questionnaire tool was distributed and the data was collected using the psychological well-being scale, the spiritual well-being scale, and the World Health Organization Quality of Life scale - BREF during the period between March 28 and August 10, 2023.